Quality & Testing
How to read a COA.
A certificate of analysis (COA) is the test report for one specific production lot. It is not marketing material — it is the laboratory’s own document, with the lot’s measured results printed next to the specification each result had to meet. Every lot we sell has one, and every certificate is published on our Lab Reports page. This guide walks through a real certificate, section by section, so you can check a lot yourself in about a minute.
01 · Start here
The lot number
At the top of the certificate you will find the lot number, the analysis date and the report number. The lot number is the thread that ties the document to a physical vial: it is the same number printed on the vial label. If the lot number on a certificate does not match the lot number on your vial, that certificate is not your lot’s document — find the matching row in the lot table instead.
02 · Who stands behind it
The laboratory, and the maker
Our certificates are issued by Horizon Analytical, a third-party testing laboratory in the United States. The header names the manufacturer the lot was produced for — Privilege Bio Labs, our production partner — under “Brand / Distributed by.” Each report is also searchable on the laboratory’s own website (horizonanalytical.com) and carries a “Scan to Validate” code, so a certificate can be checked with the lab directly, without taking our word for anything.
03 · Identity
Is it the compound on the label?
The first result on the certificate is the compound test. Using mass spectrometry, the laboratory measures the material’s molecular mass and matches it against the known mass of the named compound — the certificate prints the compound’s CAS number, formula and molecular weight alongside, so the identification can be cross-checked against public chemical records (a PubChem CID is listed as well). A match here means the vial contains the compound it claims to contain.
04 · Quantity
Is the vial filled to spec?
Below identity, the certificate reports the measured content of the vial against its labelled quantity. On the published certificate for lot DPS-1507786, for example, a 10 mg vial measured 9.96 mg. Small deviations are normal in lyophilized (freeze-dried) production; what matters is that the number is measured and printed, lot by lot, rather than assumed.
05 · Purity
How much of it is the compound?
Purity is measured by liquid chromatography (UPLC/HPLC), which separates everything in the sample so the target compound’s share can be measured. The certificate prints the specification — greater than 98% — next to the lot’s actual result, and includes the chromatogram itself: one dominant peak is the compound; the purity figure is that peak’s share of the total. The lots published on this site report purity between 99.1% and 99.99%.
06 · Endotoxin
The contamination screen
The final page of the certificate reports the bacterial endotoxin test. Endotoxins are fragments of bacterial cell walls that can be present in improperly controlled production; the test measures the sample against the laboratory’s limit and reports the outcome on the certificate. It is the quiet line of the report — and one of the first things an experienced buyer looks for.
07 · The honest limits
What a COA does not say
A certificate documents one lot’s identity, content and purity on the day it was analysed. It is not a statement about safety or effects, and it is not a promise about any other lot — which is exactly why every lot gets its own certificate, and why we publish all of them rather than a single “representative” report. If your lot number returns no certificate in the table, contact us before anything else and we will trace it with the laboratory.
All PEVELIS products are sold for laboratory research use only. Not for human or veterinary use. Not a drug, supplement, food or cosmetic. These statements have not been evaluated by the FDA.